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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of fungal keratitis
ncRNA name hsa-miR-451a
ncRNA Category miRNA
Disease name fungal keratitis
Species Homo sapiens
Tissues/Cell_line corneas
Methods RNA-seq, qRT-PCR
Expression pattern up-regulated
Functional description The highly dysregulated miRNAs (miR-511-5p, miR-142-3p, miR-155-5p, and miR-451a) may regulate wound healing as they were predicted to specifically target wound inflammatory genes. The increased expression of miR-451a in keratitis correlated with reduced expression of its target, macrophage migration inhibitory factor, suggesting possible regulatory functions.
PubMed ID 26720440
Year 2015
Title Human Corneal MicroRNA Expression Profile in Fungal Keratitis.
Drug-related ncRNA NO

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